Dosage for toxicity during chronic therapy : for adults, 6 vials (228mg) usually is adequate to reverse most cases of toxicity. If rounding is required, round to the nearest tenth.) Dosing (adults): IVPB: 0 to 1 mg/50 ml D5W or NS over 10 minutes. MeSH If patient is < 60kg give 0.01 mg/kg over 10 minutes. Adverse reactions: sinus bradyarrhythmias; AV block; N/V/D; yellow vision and hallucinations; supra and ventricular arrhythmias. The net effect is to shift the equilibrium away from binding of digoxin to its receptors in the body, thereby reversing its effects. Reconstitution/preparation techniques: The manufacturer product information should be consulted. Use Alaris LVP with Guardrails and select amIODAROne LOAD - = 60 kg in Critical Care Adult or Coronary Care Unit profile. Thallium-201 is injected at midpoint (3 minutes) of infusion. Add 3 mL of Cordarone I.V. (150 mg) to 100 mL D5W. The patient is now taking nothing by mouth (NPO), and the physician would like to switch to intravenous (IV) amiodarone. You've successfully added to your alerts. Use carton to protect contents from light until used. (If given IVPush-admin over at least 5 min).PSVT: (For patients not on digoxin): 0.25 to 0.5 mg IV. The North American Society for Pacing and Electrophysiology (NASPE) recommends amiodarone as the antiarrhythmic agent of choice in patients who have survived sustained ventricular tachyarrhythmias, particularly those with left ventricular dysfunction.4. Attempts to substitute other antiarrhythmic agents when this drug must be stopped will be made difficult by the gradually, but unpredictably, changing body burden of this drug. The recommended starting dose of Cordarone I.V. Patients with a known predisposition to bradycardia or AV block should be treated with intravenous amiodarone in a setting where a temporary pacemaker is available. Although the frequency of such proarrhythmic events does not appear greater with this drug than with many other agents used in this population, the effects are prolonged when they occur. (Glass bottle or polyolefin container) Because a typical oral amiodarone loading dose for ventricular arrhythmia starts with 800-1600 mg/day and for atrial fibrillation starts with 600-800 mg/day, I would assume that for one reason or another a decision was made not to load this patient. 2 0 obj infusion: 140 mcg/kg/minute for 6 minutes using syringe or columetric infusion pump; total dose: 0.84 mg/kg. Copyright 2023 American Academy of Family Physicians. Note: Decrease dose in patients with CHF, elderly, hepatic disease. HEPATOTOXICITY: Liver injury is common with this drug, but is usually mild and evidenced only by abnormal liver enzymes. Hepatic impairment: Maximum daily dose: 1200 mg. endobj is about 1000 mg over the first 24 hours of therapy, delivered by the following infusion regimen: First Rapid: 150 mg The maintenance infusion of up to 0.5 mg/min can be cautiously continued for 2 to 3 weeks regardless of the patient's age, renal function, or Left-ventricular function. Copyright 2021 GlobalRPH - Web Development by. F~GMlILIvau88}]nv9W_%o"v2=Wo- hh When switching from another antiarrhythmic, initiate a 200 mg dose 6-12 hours after stopping former agents, 3-6 hours after stopping procainamide. Clipboard, Search History, and several other advanced features are temporarily unavailable. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.
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