Other studies have shown that after hyperthyroidism treatment patients have a 32% increased risk of obesity and most of this weight gain occurs in the first 2 years after therapy (9). I do agree with you for that MMI isn't a steroid. I lost 5 pounds in 3 days, not doing any exercise and eating regularly. A 29-year-old male patient who has been previously healthy, on no medications, presented for weight loss during the last 6 months. You may also find benefit in trying to reduce inflammation if your hyperthyroidism is caused by Graves disease (which is an autoimmune disease) with some strategies such as these. I've lost weight gradually because I am more active, eat less and am aiming to lose the 16 lbs I put on when I was on the drug . Do not give this medicine to a child without medical advice. Aplasia cutis congenita has been reported as a possible teratogenic effect of methimazole therapy in multiple case reports. Use methimazole regularly to get the most benefit, even if you feel fine or have no symptoms of hyperthyroidism. Methimazole-induced myositis occurring independently of such reactions was rarely stated. Welcome to my website! Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Methimazole, the antithyroid-blocking medication used to treat hyperthyroidism, can lead to weight gain in certain individuals. Do not share this medicine with others. But blocking thyroid production, in a perfect way, is easier said than done. A 29-year-old male patient who has been previously healthy, on no medications, presented for weight loss during the last 6 months. But, on the other hand, we also want to balance thyroid hormone to prevent weight gain, depression and cholesterol issues (all side effects and symptoms of hypothyroidism or an indication that your body is swinging from hyperthyroidism to hypothyroidism). Therefore, we raise the awareness regarding a rare side effect of methimazole: myositis. However, I couldn't help but started noticing weight gain. Read our editorial policy. Three months ago, in December my doctor had me reduce reduced dose to 10 mg. No problem, I felt good for two more months and maintaining with my normal weight until suddenly about 4 weeks ago I started losing weight again. Always speak to your doctor before acting and in cases of emergency seek Several conditions can cause it, including Plummers disease, Graves disease, and thyroiditis. There was no evidence of either neoplasm or trauma, as both can cause eosinophilic pseudo tumor (4). No wonder so many people seem to be talking about Ozempic, an injectable drug approved by the . The chemical formula is C 4 H 6 N 2 S. Molecular weight is 114.16. Seven out of 10 people in the U.S. are overweight, many carrying belly fat that is difficult to shed. Two weeks after stopping methimazole, the fever reappeared associated with left gluteal swelling and mild erythema over the involved area. Tapazole (methimazole)." Blood and urine cultures were negative. PEOPLE spoke to Ania Jastreboff M.D., PhD., and obesity medicine physician scientist at Yale, about Ozempic, Wegovy and what happens when patients stop taking the medications."Not everybody needs the highest dose, but if you want to maintain the weight reduction that you achieved, you have to continue taking the . Store at room temperature away from moisture and heat. The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported. The onset of aplastic anemia (pancytopenia) or agranulocytosis may occur in hours to days. FOIA It has been shown in studies that all treatments for hyperthyroidism result in marked weight gain (8). methimazole, propylthiouracil, Tapazole, potassium iodide, reserpine. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Learn which foods you should avoid if you have thyroid disease of any type. Pandey S, Kushwaha RS, Mehndiratta P & Mehndiratta MM. As for polymyositis associated with Graves' disease, it is uncommon and occurs in the background of a positive family history of autoimmune diseases and positive antinuclear antibodies (2). As a result of stopping her medication, she had developed thyroid storm, a life-threatening condition in which body temperature, heart rate, and blood pressure can rise to dangerous levels . There are very few cases reporting the association between carbimazole therapy and myositis (2). Blocking your thyroid will result in some suppression of normal metabolic function. Patient information was obtained from Thyroid Clinic Database at the University Hospitals Birmingham NHS Foundation Trust. 3 years ago, Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). This slows down the metabolic processes in your body, which reduces excess weight and fat mass (like belly fat). The thyroid gland impacts our health in a number of ways. Methimazole is a medication that treats hyperthyroidism, or high thyroid levels in your body. Two weeks after stopping methimazole (on admission to the hospital) Two months after stopping methimazole; TSH: 0.35-4.94 <0.005: 0.0001 <0.0005: Free T 4: 0.7-1.48 ng/dl: 2.6 . Maintaining the rate at which you digest fats and carbohydrates, controlling your body temperature. Methimazole may also be used for purposes not listed in this medication guide. In drug-induced lupus, the symptoms usually appear within a month of starting therapy. How to Lose Weight After Stopping Singulair. 1Department of Endocrinology, Saint Georges University Medical Center, University of Balamand, Beirut, Lebanon, 2Department of Family Medicine, Saint Georges University Medical Center, University of Balamand, Beirut, Lebanon, 3Department of Infectious Diseases, Saint Georges University Medical Center, University of Balamand, Beirut, Lebanon, 4Department of General Surgery, Saint Georges University Medical Center, University of Balamand, Beirut, Lebanon, 5Department of Pathology, Saint Georges University Medical Center, University of Balamand, Beirut, Lebanon, 6Department of Gastroenterology, Saint Georges University Medical Center, University of Balamand, Beirut, Lebanon. Advertising on our site helps support our mission. A small change in your dose may be sufficient to restore some thyroid function (without causing the symptoms of hyperthyroidism) which can help manage your weight. Unable to lose weight after discontinuation of methimazole? That's why I asked. appropriate medical assistance immediately. I felt good for two more moths with my normal weight until suddenly 4 weeks ago I started loosing weight agin. Notes on Weight loss after reduced methimazole dose? Take your doses at regular intervals. Treatment of hyperthyroidism commonly results in weight gain, but the extent of weight gain is not well known. It means that it is entirely possible that taking methimazole may block the normal thyroid function in the body and lead to weight gain. Follow all directions on your prescription label. Signs of inflammation of the gluteus maximus muscles bilaterally, more so on the left (blue arrow), and the surrounding fascia (red arrow) are indicated.