Fried, M.; Navarro, V.; Afdhal, N. et al. Milk thistle has been used to treat disorders of the liver and gallbladder for at least 2,000 years. Milk thistle is most often used for various liver conditions, like hepatitis and fatty liver disease. . Anyone have experience with Milk Thistle for OCD/Anxiety? People sometimes use milk thistle for hepatitis C, a viral infection of the liver. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health. You may report side effects to FDA at 1-800-FDA-1088. People who have diabetes or endometriosis should check with a doctor before using milk thistle. The terms "milk thistle" and "silymarin" are often used interchangeably. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. If we combine this information with your protected If you choose to use milk thistle, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Depression and anxiety are associated with increased risk of developing AD. . It may have protective effects on the liver, preventing damage. Available for Android and iOS devices. People may also find it painful and worry about its effects on their appearance. Research on milk thistle use for specific conditions shows: Milk thistle might play a role in treating certain liver conditions. Finally, those with hormone-sensitive conditions, including certain cancers, may need to avoid using milk thistle. 2020;10(3):236-244. doi:10.1016/j.jtcme.2020.02.003. Effects of Silybum marianum (L.) Gaertn. Some supplements are close to chemicals in efficacy like saffron (standardized extract) for depression and magnolia bark extract for anxiety. N-Acetylcysteine In clinical trials, milk thistle appears to be well tolerated in recommended doses. Silymarin, an active component of milk thistle, may improve liver function and reduce symptoms of cirrhosis, or scarring of the liver. One of the active ingredients in milk thistle called silymarin is extracted from the plant's seeds. Researchers also have found that milk thistle improved insulin resistance, a key part of type 2 diabetes. Milk thistle may interact with certain medications and supplements. Epub 2023 Mar 4. It could interact with many drugs, including some that treat high cholesterol, infections, insomnia, and blood pressure. JAMA. However, the results from studies have been mixed, and not all have found milk thistle extract to have a beneficial effect on liver disease. Milk thistle benefits: Liver, skin, cholesterol, weight loss, and more Phytother Res. Silymarin: not just another antioxidant - PubMed Call your doctor for medical advice about side effects. Certain people should take precautions when using milk thistle, and others may need to avoid it altogether. Milk thistle seems to have few side effects, even when taken for several years. A double-blind controlled study. Ebrahimpour, K.; Gargari, B.; Mobasseri, M. et al. Nanjan MJ, Betz J. Resveratrol for the management of diabetes and its downstream pathologies. Milk thistle can cause an allergic reaction, including a severe, potentially life-threatening allergic reaction (anaphylaxis). It's also proven useful in treating skin that's been damaged by radiation during breast cancer treatment. Not only does this help prevent cirrhoris, but may also be advantageous for those living with hepatitis or other liver diseases. Below is a short list of 4 widely available and very affordable herbs with some serious natural health benefits for OCD sufferers: Before introducing milk thistle into your diet, new supplements or any other herbs for OCD for that matter you should consult your physician. Milk thistle. Dupuis ML, Conti F, Maselli A, et al. The benefits of milk thistle can be attributed to its anti-inflammatory and antioxidant effects. Summary Initial test-tube and animal studies have shown that milk thistle has some promising characteristics that could make it useful for protecting brain function. Can Milk Thistle Help People With Diabetes? de Avelar CR, Pereira EM, de Farias Costa PR, et al. The study researchers hypothesize that milk thistle's antioxidant qualities make it a good candidate for treating conditions like cancer, hepatitis, NAFLD, diabetes, depression, and heart disease. Do not use extra milk thistle to make up the missed dose. Zhang Z, Wu H, Qi S, Tang Y, Qin C, Liu R, Zhang J, Cao Y, Gao X. Int J Environ Res Public Health. 8600 Rockville Pike By lowering LDL "bad" cholesterol levels, milk thistle may lower the chance of developing heart disease. National Cancer Institute PDQ Integrative, Alternative, and Complementary Therapies Editorial Board. An official website of the United States government. Milk thistle has been used for a range of psychiatric disorders including methamphetamine abuse and obsessive compulsive disorder. information is beneficial, we may combine your email and website usage information with In one such study, a 45-day course of silymarin, the active component of milk thistle, increased antioxidant capacity and reduced generalized inflammation in adults with type 2 diabetes compared with a placebo. Dosage and side effects. Milk thistle is generally thought to be safe, but you still may experience side effects when taking it. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. However, there is no solid evidence that supports these claims. Although rare, milk thistle may trigger a number of common and mild side effects. Bunchorntavakul C, Wootthananont T, Atsawarungruangkit A. Do not use this product without medical advice if you are breast-feeding a baby. Accessed Oct. 30, 2020. According to researchers, these findings suggest that silymarin may improve diabetes symptoms like oxidative stress and inflammation. Consult with your healthcare provider if you experience these and other side effects to find out the best way to proceed. About curcumin, it isn't usually a problem but if you're on IMAOs you may like to read a bit before taking high doses. Epub 2016 Dec 22. Summary Milk thistle extract may help protect the liver against damage caused by disease or poisoning, though more research is needed. Researchers believe that silymarin reduced the oxidative stress traditionally attributed with diabetes (7). . Comparing Natural Remedies for OCD to Standard OCD Treatment JAMA. A 2010 review by researchers found that black . Questions? Prasad RR, Paudel S, Raina K, Agarwal R. Silibinin and non-melanoma skin cancers. However, the review's authors warned that the quality of the studies was poor and that more research is needed before milk thistle should be recommended for use. Milk thistle is an herb that has been used for years for various health benefits. Scan J Gastroenterol. Subjects were assessed with the National Institute of Mental Health Trichotillomania Severity Scale (primary outcome), the Massachusetts General Hospital Hair Pulling Scale, Clinical Global Impression scale, and measures of depression, anxiety, and psychosocial . Silibinin significantly attenuated anxiety/depression-like behaviors caused by A1-42-treatment as shown in tail suspension test (TST), elevated plus maze (EPM) and forced swimming tests (FST).
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